Win 58237
Win 58237 is a cyclic nucleotide phosphodiesterase (PDE) inhibitor, with Ki of 170 nM for PDE V, possessing vasorelaxant activity.
Product Specifications
CAS Number
158001-76-4
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Win_58237.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(N(C3CCCC3)N=C2C)NC(C4=CC=NC=C4)=N1
Molecular Formula
C16H17N5O
Molecular Weight
295.34
References & Citations
[1]Silver PJ, et al. Cyclic GMP potentiation by WIN 58237, a novel cyclic nucleotide phosphodiesterase inhibitor. J Pharmacol Exp Ther. 1994 Dec;271 (3) :1143-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
B9140 96 Tests
Bone Morphogenetic Protein 7 (BMP-7) Canine ELISA Kit
Sign In for Pricing
View Details 