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ACAT-IN-1 cis isomer

ACAT-IN-1 cis isomer is a potent ACAT inhibitor with an IC50 of 100 nM.

Product Specifications

CAS Number

145961-79-1

UNSPSC

12352005

Target

Acyltransferase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Benzeneacetamide,_N-[2,3-dihydro-2-_4-hydroxyphenyl_-1H-inden-1-yl]-_alpha_-phenyl-,_cis-.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@H]1[C@@H](C2=CC=C(O)C=C2)CC3=C1C=CC=C3)C(C4=CC=CC=C4)C5=CC=CC=C5

Molecular Formula

C29H25NO2

Molecular Weight

419.51

References & Citations

[1]Vaccaro W, et al. Inhibitors of Acyl CoA:Cholesterol Acyltransferase. J. Med. Chem., 1996, 39 (8), pp 1704–1719

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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