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Tulopafant

Tulopafant is a platelet activating factor (PAF) antagonist.

Product Specifications

CAS Number

116289-53-3

Product Name Alternative

RP 59227

UNSPSC

12352005

Hazard Statement

H302

Target

Platelet-activating Factor Receptor (PAFR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Tulopafant.html

Solubility

10 mM in DMSO

Smiles

O=C(C(C=C1)=C2N1C(C3=CC=CN=C3)SC2)NC4=CC=CC(C(C5=CC=CC=C5)=O)=C4

Molecular Formula

C25H19N3O2S

Molecular Weight

425.50

Precautions

P264-P270-P330-P501

References & Citations

[1]Auchampach JA, et al. Effect of the platelet-activating factor antagonist RP 59227 (Tulopafant) on myocardial ischemia/reperfusion injury and neutrophil function. Basic Res Cardiol. 1998 Oct;93 (5) :361-71.|[2]O'Hair DP, et al. Tulopafant, a PAF receptor antagonist, increases capillary patency and prolongs survival in discordant cardiac xenotransplants. J Lipid Mediat. 1993 May;7 (1) :79-84.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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