Tulopafant
Tulopafant is a platelet activating factor (PAF) antagonist.
Product Specifications
CAS Number
116289-53-3
Product Name Alternative
RP 59227
UNSPSC
12352005
Hazard Statement
H302
Target
Platelet-activating Factor Receptor (PAFR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Tulopafant.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C=C1)=C2N1C(C3=CC=CN=C3)SC2)NC4=CC=CC(C(C5=CC=CC=C5)=O)=C4
Molecular Formula
C25H19N3O2S
Molecular Weight
425.50
Precautions
P264-P270-P330-P501
References & Citations
[1]Auchampach JA, et al. Effect of the platelet-activating factor antagonist RP 59227 (Tulopafant) on myocardial ischemia/reperfusion injury and neutrophil function. Basic Res Cardiol. 1998 Oct;93 (5) :361-71.|[2]O'Hair DP, et al. Tulopafant, a PAF receptor antagonist, increases capillary patency and prolongs survival in discordant cardiac xenotransplants. J Lipid Mediat. 1993 May;7 (1) :79-84.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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