Pratosartan
Product Specifications
UNSPSC Description
Pratosartan is a selective angiotensin II receptor antagonist.
Target Antigen
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cardiovascular Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Pratosartan.html
Solubility
10 mM in DMSO
Smiles
O=C1CCCCC2=C1N(CC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3)C(CCC)=N2
Molecular Weight
426.51
References & Citations
[1]Sonegawa M, et al. Synthesis and pharmacological activity of the metabolites of Pratosartan. Chem Pharm Bull (Tokyo). 2006 Jun;54(6):782-7.|[2]Ogihara T, et al. Clinical efficacy of a new angiotensin II type 1 receptor blocker, pratosartan, in hypertensive patients. Hypertens Res. 2008 Feb;31(2):281-7.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101574/Pratosartan-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101574/
Clinical Information
Phase 3
CAS Number
153804-05-8
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