Pratosartan

Pratosartan is a selective angiotensin II receptor antagonist.

Product Specifications

CAS Number

[153804-05-8]

Product Name Alternative

FW 7203; KD 3-671; KT 3671

UNSPSC

12352005

Target

Angiotensin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cardiovascular Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Pratosartan.html

Solubility

10 mM in DMSO

Smiles

O=C1CCCCC2=C1N(CC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3)C(CCC)=N2

Molecular Formula

C25H26N6O

Molecular Weight

426.51

References & Citations

[1]Sonegawa M, et al. Synthesis and pharmacological activity of the metabolites of Pratosartan. Chem Pharm Bull (Tokyo) . 2006 Jun;54 (6) :782-7.|[2]Ogihara T, et al. Clinical efficacy of a new angiotensin II type 1 receptor blocker, pratosartan, in hypertensive patients. Hypertens Res. 2008 Feb;31 (2) :281-7.