Pratosartan
Pratosartan is a selective angiotensin II receptor antagonist.
Product Specifications
CAS Number
[153804-05-8]
Product Name Alternative
FW 7203; KD 3-671; KT 3671
UNSPSC
12352005
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cardiovascular Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Pratosartan.html
Solubility
10 mM in DMSO
Smiles
O=C1CCCCC2=C1N(CC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3)C(CCC)=N2
Molecular Formula
C25H26N6O
Molecular Weight
426.51
References & Citations
[1]Sonegawa M, et al. Synthesis and pharmacological activity of the metabolites of Pratosartan. Chem Pharm Bull (Tokyo) . 2006 Jun;54 (6) :782-7.|[2]Ogihara T, et al. Clinical efficacy of a new angiotensin II type 1 receptor blocker, pratosartan, in hypertensive patients. Hypertens Res. 2008 Feb;31 (2) :281-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
AT1 Receptor
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