ATM-3507 (trihydrochloride)
ATM-3507 trihydrochloride is a potent tropomyosin inhibitor with IC50s from 3.83-6.84 μM in human melanoma cell lines.
Product Specifications
CAS Number
[2438679-30-0]
UNSPSC
12352005
Target
Myosin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atm-3507-trihydrochloride.html
Solubility
10 mM in DMSO|10 mM in H2O
Smiles
O=C(C1=CC=CC(OC2=CC3=C(N(CCCN4CCN(C)CC4)C(C)=C3C)C=C2)=C1)N5CCN(CCC6=CC=C(F)C=C6)CC5.Cl.Cl.Cl
Molecular Formula
C37H49Cl3FN5O2
Molecular Weight
721.17
References & Citations
[1]Currier MA, et al. Identification of Cancer-Targeted Tropomyosin Inhibitors and Their Synergy with Microtubule Drugs.Mol Cancer Ther. 2017 Aug;16 (8) :1555-1565.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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