Forphenicine
Forphenicine is a bacterial metabolite that is found in S. fulvoviridis and an inhibitor of alkaline phosphatase. Forphenicine inhibits the growth of HL-60 leukemia cells at 10 µM. Forphenicine also increases survival in a guinea pig model of experimental autoimmune encephalomyelitis (EAE) [1][2].
Product Specifications
CAS Number
57784-96-0
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/forphenicine.html
Smiles
OC([C@H](C1=CC(O)=C(C=C1)C=O)N)=O
Molecular Formula
C9H9NO4
Molecular Weight
195.17
References & Citations
[1]Miura K, et al. Effects of enzyme inhibitors in inhibiting the growth and inducing the differentiation of human promyelocytic leukemia cells, HL-60. J Antibiot (Tokyo) . 1986 May;39 (5) :734-5. |[2]Aoyagi T, et al. Forphenicine, and inhibitor of alkaline phosphatase produced by actinomycetes. J Antibiot (Tokyo) . 1978 Mar;31 (3) :244-6.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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