Nalidixic acid (Standard)

Nalidixic acid (Standard) is the analytical standard of Nalidixic acid. This product is intended for research and analytical applications. Nalidixic acid, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria[1].

Product Specifications

CAS Number

[389-08-2]

UNSPSC

12352005

Target

Antibiotic; Bacterial; Reference Standards; Topoisomerase

Type

Reference Standards

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/nalidixic-acid-standard.html

Purity

99.98

Smiles

O=C(C1=CN(CC)C2=C(C=CC(C)=N2)C1=O)O

Molecular Formula

C12H12N2O3

Molecular Weight

232.24

References & Citations

[1]antibiotic, DNA gyrase, susceptible bacteria, Escherichia coli, Klebsiella pneuiiioniae, Aerobacter aeroyenes, Proteus spp, Salmonella spp.|[2]Anna Fàbrega, et al. Mechanism of Action of and Resistance to Quinolones. Microb Biotechnol