ODN 6016 (sodium)

ODN 6016 sodium is a CpG-A oligonucleotides. ODN 6016 sodium can induce IFN-α production, and can be used for researching immune disorders including immunodeficiency caused by HIV-1. ODN 6016 sequence: T-sp-C-G-A-C-G-T-C-G-T-G-G-sp-G-sp-G-sp-G[1][2].

Product Specifications

UNSPSC

12352208

Target

IFNAR

Type

Oligonucleotides

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/odn-6016-sodium.html

Purity

99.26

Solubility

10 mM in H2O

Smiles

[ODN6016(sodium)]

Molecular Weight

4729.3 (free acid)

References & Citations

[1]Ries M, et al. Identification of novel oligonucleotides from mitochondrial DNA that spontaneously induce plasmacytoid dendritic cell activation. J Leukoc Biol. 2013 Jul;94 (1) :123-35.|[2]Tennert K, et al. Elevated CD40 ligand silences α interferon production in an HIV-related immune reconstitution inflammatory syndrome. AIDS. 2013 Jan 14;27 (2) :297-9.