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CB2R-IN-1

CB2R-IN-1 is a potent cannabinoid CB2 receptor inverse agonist with a Ki of 0.9 nM.

Product Specifications

CAS Number

1257555-79-5

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Cannabinoid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/CB2R-IN-1.html

Solubility

10 mM in DMSO

Smiles

O=S(C(F)(F)F)(NCC1(CCC)CCN(S(=O)(C(N2S(=O)(C3=NC=CC=C3)=O)=CC4=C2C=CC=C4)=O)CC1)=O

Molecular Formula

C23H27F3N4O6S3

Molecular Weight

608.67

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Tong L, et al. Expansion of SAR studies on triaryl bis sulfone cannabinoid CB2 receptor ligands. Bioorg Med Chem Lett. 2010 Nov 15;20 (22) :6785-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CB2

Frequently Asked Questions

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