MK-6913
MK-6913 (Tetrahydrofluoroene 52) is a potent and selective estrogen receptor β agonist.
Product Specifications
CAS Number
[1398510-92-3]
Product Name Alternative
Tetrahydrofluoroene 52
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Tetrahydrofluoroene_52.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C2C3=CC=C(N(C(C)(C)C)N=N4)C4=C3C[C@]2(CCOC5=CC=CC=C5)CC1
Molecular Formula
C25H27N3O2
Molecular Weight
401.50
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Matthew L. Maddess, et al. Enantioselective Synthesis of a Highly Substituted Tetrahydrofluorene Derivative as a Potent and Selective Estrogen Receptor Beta Agonist. Org Process Res Dev. 2014 Mar 3;18 (4) : 528–538.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Curated Selection
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