H100
H100 is a Cl- transport inhibitor, with partial effects against both the NaK2Cl cotransporter and the Band 3 anion exchanger, but no effect against KCl cotransporter, in human erythrocytes.
Product Specifications
CAS Number
[643727-55-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Chloride Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/H100.html
Purity
99.17
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(O)C1=CC(N2C=CC=C2)=C(OC3=CC=C(OC)C=C3)C(S(=O)(N)=O)=C1
Molecular Formula
C18H16N2O6S
Molecular Weight
388.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Culliford S1, et al. Specificity of classical and putative Cl (-) transport inhibitors on membrane transport pathways in human erythrocytes. Cell Physiol Biochem. 2003;13 (4) :181-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
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