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UK-157147

UK-157147 is a substrate for UDP-glucuronosyltransferases (UGT1A1) with a Km value of 105 μM.

Product Specifications

CAS Number

162704-20-3

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

UGT

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/UK-157147.html

Solubility

10 mM in DMSO

Smiles

O=C1C=CC(O[C@H]2[C@](C)(O)C(C)(C)OC3=CC=C(S(=O)(C4=CC=CC(O)=C4)=O)C=C23)=NN1C

Molecular Formula

C23H24N2O7S

Molecular Weight

472.51

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Ethell BT, et al. Use of cloned and expressed human UDP-glucuronosyltransferases for the assessment of human drug conjugation and identification of potential drug interactions. Drug Metab Dispos. 2001 Jan;29 (1) :48-53.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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