UK-157147
UK-157147 is a substrate for UDP-glucuronosyltransferases (UGT1A1) with a Km value of 105 μM.
Product Specifications
CAS Number
[162704-20-3]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
UGT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/UK-157147.html
Solubility
10 mM in DMSO
Smiles
O=C1C=CC(O[C@H]2[C@](C)(O)C(C)(C)OC3=CC=C(S(=O)(C4=CC=CC(O)=C4)=O)C=C23)=NN1C
Molecular Formula
C23H24N2O7S
Molecular Weight
472.51
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Ethell BT, et al. Use of cloned and expressed human UDP-glucuronosyltransferases for the assessment of human drug conjugation and identification of potential drug interactions. Drug Metab Dispos. 2001 Jan;29 (1) :48-53.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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