CP-96486
CP-96486 is a potent and orally active leukotriene D4 (LTD4) /platelet activating factor (PAF) receptor antagonist with Kis of 20 and 24 nM, respectively.
Product Specifications
CAS Number
139401-45-9
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/CP-96486.html
Solubility
10 mM in DMSO
Smiles
CC(N1C2=CC=C(OCC3=CC(/C=C/C4=NC5=CC(Cl)=CC=C5C=C4)=CC=C3)C=C2)=NC6=C1C=CN=C6
Molecular Formula
C31H23ClN4O
Molecular Weight
502.99
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]A.Marfat, et al. The discovery of CP-96,021 and CP-96,486, balanced, combined, potent and orally active leukotriene D4 (LTD4) /platelet activating factor (PAF) receptor antagonists.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
LTD4/CysLT1
Frequently Asked Questions
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