CP-96486

CP-96486 is a potent and orally active leukotriene D4 (LTD4) /platelet activating factor (PAF) receptor antagonist with Kis of 20 and 24 nM, respectively.

Product Specifications

CAS Number

[139401-45-9]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Leukotriene Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/CP-96486.html

Solubility

10 mM in DMSO

Smiles

CC(N1C2=CC=C(OCC3=CC(/C=C/C4=NC5=CC(Cl)=CC=C5C=C4)=CC=C3)C=C2)=NC6=C1C=CN=C6

Molecular Formula

C31H23ClN4O

Molecular Weight

502.99

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]A.Marfat, et al. The discovery of CP-96,021 and CP-96,486, balanced, combined, potent and orally active leukotriene D4 (LTD4) /platelet activating factor (PAF) receptor antagonists.