KW-8232 free base
KW-8232 free base, an orally active anti-osteoporotic agent, and can reduces the biosynthesis of PGE2[1].
Product Specifications
CAS Number
170365-25-0
UNSPSC
12352005
Target
Prostaglandin Receptor; SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/KW-8232_free_base.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
O=C(C(N1CCN(C)C)=C(C(C2=CC=C(O)C=C2)C3=CC=C(O)C=C3)C4=C1C=CC=C4)N5CCN(C6=CC=CC=C6Cl)CC5
Molecular Formula
C36H37ClN4O3
Molecular Weight
609.16
References & Citations
[1]Uchii M, et al. Effect of KW-8232, a novel anti-osteoporotic agent, on bone loss in sciatic neurectomized rats. Jpn J Pharmacol. 1998 Oct;78 (2) :241-3.|[2]Shiwei Wang, et al. A Transferable Deep Learning Approach to Fast Screen Potent Antiviral Drugs against SARS-CoV-2. bioRxiv. 2020.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EP
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