KW-8232 free base

KW-8232 free base, an orally active anti-osteoporotic agent, and can reduces the biosynthesis of PGE2[1].

Product Specifications

CAS Number

[170365-25-0]

UNSPSC

12352005

Target

Prostaglandin Receptor; SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection; GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/KW-8232_free_base.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

O=C(C(N1CCN(C)C)=C(C(C2=CC=C(O)C=C2)C3=CC=C(O)C=C3)C4=C1C=CC=C4)N5CCN(C6=CC=CC=C6Cl)CC5

Molecular Formula

C36H37ClN4O3

Molecular Weight

609.16

References & Citations

[1]Uchii M, et al. Effect of KW-8232, a novel anti-osteoporotic agent, on bone loss in sciatic neurectomized rats. Jpn J Pharmacol. 1998 Oct;78 (2) :241-3.|[2]Shiwei Wang, et al. A Transferable Deep Learning Approach to Fast Screen Potent Antiviral Drugs against SARS-CoV-2. bioRxiv. 2020.