ICI 153110

ICI 153110 is an orally active phosphodiesterase inhibitor with both vasodilating and inotropic properties which is designed for the treatment of congestive cardiac failure.

Product Specifications

CAS Number

[87164-90-7]

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ICI_153110.html

Solubility

10 mM in DMSO

Smiles

O=C1CCC(/C=C/C2=CC=NC=C2)=NN1

Molecular Formula

C11H11N3O

Molecular Weight

201.22

References & Citations

[1]Westwood FR, et al. Pathologic changes in blood vessels following administration of an inotropic vasodilator (ICI 153,110) to the rat. Fundam Appl Toxicol. 1990 May;14 (4) :797-809.