Amphethinile
Amphethinile is an anti-tubulin agent. The affinity constant for the association (Ka) of Amphethinile with tubulin is 1.3 μM.
Product Specifications
CAS Number
[91531-98-5]
Product Name Alternative
Amphetinile; CRC 82-07
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Amphethinile.html
Solubility
10 mM in DMSO
Smiles
N#CC1=C(N)NC2=C1C=C(SC3=CC=CC=C3)C=C2
Molecular Formula
C15H11N3S
Molecular Weight
265.33
References & Citations
[1]McGown AT, et al. Interaction of the novel agent amphethinile with tubulin. Br J Cancer. 1989 Jun;59 (6) :865-8.|[2]McGown AT, et al. Pre-clinical studies of a novel anti-mitotic agent, amphethinile. Br J Cancer. 1988 Feb;57 (2) :157-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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