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CX-157

CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3 ng/mL.

Product Specifications

CAS Number

[205187-53-7]

UNSPSC

12352005

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/CX-157.html

Solubility

10 mM in DMSO

Smiles

FC(F)(F)COC1=CC(OC2=CC(F)=CC=C2S3(=O)=O)=C3C=C1

Molecular Formula

C14H8F4O4S

Molecular Weight

348.27

References & Citations

[1]Fowler JS, et al. Reversible inhibitors of monoamine oxidase-A (RIMAs) : robust, reversible inhibition of human brain MAO-A by CX157. Neuropsychopharmacology. 2010 Feb;35 (3) :623-31.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Curated Selection

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