CX-157
CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3 ng/mL.
Product Specifications
CAS Number
[205187-53-7]
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/CX-157.html
Solubility
10 mM in DMSO
Smiles
FC(F)(F)COC1=CC(OC2=CC(F)=CC=C2S3(=O)=O)=C3C=C1
Molecular Formula
C14H8F4O4S
Molecular Weight
348.27
References & Citations
[1]Fowler JS, et al. Reversible inhibitors of monoamine oxidase-A (RIMAs) : robust, reversible inhibition of human brain MAO-A by CX157. Neuropsychopharmacology. 2010 Feb;35 (3) :623-31.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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