ICI 211965
ICI 211965 (ZM-211965) is a selective and orally potent 5-Lipoxygenase (5-LPO) inhibitor.
Product Specifications
CAS Number
[129424-08-4]
Product Name Alternative
ZM-211965
UNSPSC
12352005
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ICI_211965.html
Solubility
10 mM in DMSO
Smiles
CCC(C1=NC=CS1)(OC)C2=CC=CC(OCC3=CC=C4C=CC=CC4=C3)=C2
Molecular Formula
C24H23NO2S
Molecular Weight
389.51
References & Citations
[1]Crawley GC, et al. Methoxytetrahydropyrans. A new series of selective and orally potent 5-lipoxygenase inhibitors. J Med Chem. 1992 Jul 10;35 (14) :2600-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-LOX
Curated Selection
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