Human VEGF-D Recombinant Protein

VEGF-D is member of the family of vascular endothelial growth factor (VEGF) proteins, which stimulate vasculogenesis and angiogenesis to restore oxygen supply to tissues. Human VEGF-D Recombinant Protein is purified vascular endothelial growth factor D produced in yeast.

Product Specifications

Synonyms

Vascular endothelial growth factor D

Gene Name

VEGFD

UniProt

O43915

Tissue Specificity

Highly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas.

Source

Yeast

Sequence

[object Object]

Applications

Cell Culture

Field of Research

Angiogenesis, Cancer, Cardiovascular, Growth Factors, Growth Factors/Hormones, Invasion/Microenvironment, Signal Transduction

Purification

Ion-exchange chromatography.

Bioactivity

In testing.

Form

Lyophilized

Function

Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.