Human IL-17A Recombinant Protein
IL-17A is a member of the IL-17 family of cytokines, whose members are involved in numerous immune regulatory functions. IL-17 induces the production of many other cytokines, chemokines, and prostaglandins. Human IL-17A Recombinant Protein is purified interleukin-17A produced in yeast.
Product Specifications
Synonyms
Interleukin-17A; IL-17; IL-17A; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8; IL17A; CTLA8; IL17
Gene Name
IL17A
UniProt
Q16552
Tissue Specificity
Restricted to activated memory T-cells.
Source
Yeast
Sequence
[object Object]
Applications
Cell Culture
Field of Research
Cytokines, Immunology, Innate Immunity, Interleukins, Macrophage/Inflammation
Purification
Ion-exchange chromatography.
Bioactivity
In testing.
Form
Lyophilized
Function
Ligand for IL17RA and IL17RC (PubMed:17911633) . The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971) . Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080) .
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Subcellular Location
Secreted.
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