Human IL-17A Recombinant Protein

IL-17A is a member of the IL-17 family of cytokines, whose members are involved in numerous immune regulatory functions. IL-17 induces the production of many other cytokines, chemokines, and prostaglandins. Human IL-17A Recombinant Protein is purified interleukin-17A produced in yeast.

Product Specifications

Synonyms

Interleukin-17A; IL-17; IL-17A; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8; IL17A; CTLA8; IL17

Gene Name

IL17A

UniProt

Q16552

Tissue Specificity

Restricted to activated memory T-cells.

Source

Yeast

Sequence

[object Object]

Applications

Cell Culture

Field of Research

Cytokines, Immunology, Innate Immunity, Interleukins, Macrophage/Inflammation

Purification

Ion-exchange chromatography.

Bioactivity

In testing.

Form

Lyophilized

Function

Ligand for IL17RA and IL17RC (PubMed:17911633) . The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971) . Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080) .