Mouse CCL3 Recombinant Protein
Chemokine ligand 3 (CCL3), also known as Macrophage inflammatory protein-1 alpha (MIP-1 alpha) is a small cytokine belonging to the CC chemokine family. CCL3/MIP-1 alpha is a chemoattractant for several different leukocytes, with varying degrees of potency (monocytes = T-cells>neutrophils>eosinophils) .
Product Specifications
Synonyms
C-C motif chemokine 3; Heparin-binding chemotaxis protein; L2G25B; Macrophage inflammatory protein 1-alpha; MIP-1-alpha; SIS-alpha; Small-inducible cytokine A3; TY-5; Ccl3; Mip1a; Scya3
Gene Name
CCL3
UniProt
P10855
Tissue Specificity
Expressed in lung, spleen, and pancreas.
Source
Yeast
Sequence
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Applications
Cell Culture
Field of Research
Antiviral Signaling, Chemokines, Immune System Diseases, Immunology, Innate Immunity, Macrophage/Inflammation
Purification
Ion-exchange chromatography.
Bioactivity
In testing.
Form
Lyophilized
Function
Monokine with inflammatory, pyrogenic and chemokinetic properties. Has a potent chemotactic activity for eosinophils. Binding to a high-affinity receptor activates calcium release in neutrophils.
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Subcellular Location
Secreted.
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