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Mouse CXCL10 Recombinant Protein

The ELR-negative CXC chemokine CXCL10 (IP-10) has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. Mouse CXCL10 Recombinant Protein is purified CXCL10 (IP-10) produced in yeast.

Product Specifications

Synonyms

C-X-C motif chemokine 10; 10 kDa interferon gamma-induced protein; Gamma-IP10; IP-10; C7; Interferon-gamma induced protein CRG-2; Small-inducible cytokine B10; Cxcl10; Crg2; Ifi10; Inp10; Scyb10

Gene Name

CXCL10

UniProt

P17515

Tissue Specificity

Expressed in the spleen, thymus, lymph nodes and liver.

Source

Yeast

Sequence

[object Object]

Applications

Cell Culture

Field of Research

Angiogenesis, Cancer, Chemokines, Immunology, Innate Immunity, Invasion/Microenvironment

Purification

Ion-exchange chromatography.

Bioactivity

In testing.

Form

Lyophilized

Function

In addition to its role as a proinflammatory cytokine, may participate in T-cell effector function and perhaps T-cell development.

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. Avoid repeated freeze-thaw cycles.

Subcellular Location

Secreted.

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