Human IL-1 beta Recombinant Protein

Human IL-1 beta

Product Specifications

Synonyms

Interleukin-1 beta; IL-1 beta; Catabolin; IL1B; IL1F2

Gene Name

IL1B

UniProt

P01584

Tissue Specificity

Expressed in activated monocytes/macrophages (at protein level) .

Source

Yeast

Sequence

[object Object]

Applications

Cell Culture

Field of Research

Atherosclerosis, Cardiovascular, Cytokines, Immunology, Innate Immunity, Interleukins, Metabolism, Obesity, Vascular Inflammation

Purification

Ion-exchange chromatography.

Bioactivity

In testing.

Form

Lyophilized

Function

Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells.