Neurodazine
Neurodazine is a neurogenic inducer, serve as a promoter of neurogenesisin pluripotent cells. Neurodazine promotes neurogenesis by activating Wnt and Shh signaling pathways.[1][2].
Product Specifications
CAS Number
937807-66-4
UNSPSC
12352005
Hazard Statement
H301, H318, H413
Target
Hedgehog; Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/neurodazine.html
Purity
99.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=CC=C(C2=C(C3=CC=C(OC)C=C3)N=C(C4=CC=C(C5=CC=CC(Cl)=C5)O4)N2)C=C1
Molecular Formula
C27H21ClN2O3
Molecular Weight
456.92
Precautions
H301, H318, H413
References & Citations
[1]Kim GH, et al. Imidazole-based small molecules that promote neurogenesis in pluripotent cells. Angew Chem Int Ed Engl. 2014 Aug 25;53 (35) :9271-4.|[2]Halder D, et al. Synthetic small molecules that induce neuronal differentiation in neuroblastoma and fibroblast cells. Mol Biosyst. 2015 Oct;11 (10) :2727-37.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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