Neurodazine

Neurodazine is a neurogenic inducer, serve as a promoter of neurogenesisin pluripotent cells. Neurodazine promotes neurogenesis by activating Wnt and Shh signaling pathways.[1][2].

Product Specifications

CAS Number

[937807-66-4]

UNSPSC

12352005

Hazard Statement

H301, H318, H413

Target

Hedgehog; Wnt

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/neurodazine.html

Purity

99.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COC1=CC=C(C2=C(C3=CC=C(OC)C=C3)N=C(C4=CC=C(C5=CC=CC(Cl)=C5)O4)N2)C=C1

Molecular Formula

C27H21ClN2O3

Molecular Weight

456.92

Precautions

H301, H318, H413

References & Citations

[1]Kim GH, et al. Imidazole-based small molecules that promote neurogenesis in pluripotent cells. Angew Chem Int Ed Engl. 2014 Aug 25;53 (35) :9271-4.|[2]Halder D, et al. Synthetic small molecules that induce neuronal differentiation in neuroblastoma and fibroblast cells. Mol Biosyst. 2015 Oct;11 (10) :2727-37.