Cyfluthrin
Cyfluthrin is a type II pyrethroid and has effects on various insects. Cyfluthrin is a modulator of Nav1.8 sodium channels by repetitive stimulation. Cyfluthrin can be applied in agriculture, veterinary, insecticide, pyrethroid and stored product[1][2].
Product Specifications
CAS Number
68359-37-5
UNSPSC
12352005
Hazard Statement
H300+H330, H362, H370, H410
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cyfluthrin.html
Purity
99.52
Solubility
DMSO : ≥ 200 mg/mL
Smiles
O=C(C1C(C)(C)C1/C=C(Cl)\Cl)OC(C#N)C2=CC=C(F)C(OC3=CC=CC=C3)=C2
Molecular Formula
C22H18Cl2FNO3
Molecular Weight
434.29
Precautions
H300+H330, H362, H370, H410
References & Citations
[1]Jin-Sung Choi, et al.Structure-activity Relationships for the Action of 11 Pyrethroid Insecticides on Rat Na v 1.8 Sodium Channels Expressed in Xenopus Oocytes.Toxicol Appl Pharmacol. 2006 Mar 15;211 (3) :233-44|[2]María-Aránzazu Martínez, et al. Oxidative Stress and Related Gene Expression Effects of Cyfluthrin in Human Neuroblastoma SH-SY5Y Cells: Protective Effect of Melatonin. Environ Res. 2019 Oct;177:108579.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Nav1.8
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