Boc-NH-PEG4-CH2CH2NH2
Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Boc-NH-PEG4-CH2CH2NH2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
811442-84-9
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/boc-nh-peg4-ch2ch2nh2.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C(OC(C)(C)C)NCCOCCOCCOCCOCCN
Molecular Formula
C15H32N2O6
Molecular Weight
336.42
Precautions
H302, H315, H319, H335
References & Citations
[1]Hans-Georg Lerchen, et al. Preparation of antibody drug conjugates of kinesin spindle protein (KSP) inhibitors with anti-TWEAKR-antibodies. WO2016207094A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers; Cleavable Linker; PEG Linkers
Available Sizes
Frequently Asked Questions
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