Boc-NH-PEG4-CH2CH2NH2

Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Boc-NH-PEG4-CH2CH2NH2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[811442-84-9]

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker; PROTAC Linkers

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/boc-nh-peg4-ch2ch2nh2.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C(OC(C)(C)C)NCCOCCOCCOCCOCCN

Molecular Formula

C15H32N2O6

Molecular Weight

336.42

Precautions

H302, H315, H319, H335

References & Citations

[1]Hans-Georg Lerchen, et al. Preparation of antibody drug conjugates of kinesin spindle protein (KSP) inhibitors with anti-TWEAKR-antibodies. WO2016207094A1.