5,6-trans-Travoprost

5,6-trans-Travoprost is the isomer of Travoprost (HY-B0584), and can be used as an experimental control. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension[1].

Product Specifications

CAS Number

[1563176-59-9]

Product Name Alternative

5,6-trans-Fluprostenol isopropyl ester; 5,6-trans-AL6221; 5,6-trans-Flu-Ipr

UNSPSC

12352005

Hazard Statement

H302

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/5-6-trans-travoprost.html

Solubility

10 mM in DMSO

Smiles

CC(C)OC(CCC/C=C/C[C@@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/[C@@H](O)COC2=CC(C(F)(F)F)=CC=C2)=O

Molecular Formula

C26H35F3O6

Molecular Weight

500.55

Precautions

H302

References & Citations

[1]M R Hellberg, et al. Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist. J Ocul Pharmacol Ther. 2001 Oct;17 (5) :421-32.