Dexetimide

Dexetimide ((+) -Benzetimide; (S) - (+) -Dexetimide; Dexbenzetimide) is a piperidine anticholinergic and a high-affinity muscarinic receptor antagonist. Dexetimide can be used in studies of parkinson's disease[1][2].

Product Specifications

CAS Number

[21888-98-2]

Product Name Alternative

(+) -Benzetimide; (S) - (+) -Dexetimide; Dexbenzetimide

UNSPSC

12352005

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dexetimide.html

Purity

99.94

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(N1)[C@@](C2CCN(CC3=CC=CC=C3)CC2)(C4=CC=CC=C4)CCC1=O

Molecular Formula

C23H26N2O2

Molecular Weight

362.46

References & Citations

[1]Speck AL, et al. The absolute configuration and crystal structure of the anticholinergic drug dexbenzetimide. Nature. 1971 Aug 20;232 (5312) :575-6.|[2]Müller-Gärtner HW, et al. Imaging muscarinic cholinergic receptors in human brain in vivo with Spect, [123I]4-iododexetimide, and [123I]4-iodolevetimide. J Cereb Blood Flow Metab. 1992 Jul;12 (4) :562-70.