Dexetimide
Product Specifications
UNSPSC Description
Dexetimide ((+)-Benzetimide; (S)-(+)-Dexetimide; Dexbenzetimide) is a piperidine anticholinergic and a high-affinity muscarinic receptor antagonist. Dexetimide can be used in studies of parkinson's disease[1][2].
Target Antigen
mAChR
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dexetimide.html
Purity
99.94
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(N1)[C@@](C2CCN(CC3=CC=CC=C3)CC2)(C4=CC=CC=C4)CCC1=O
Molecular Weight
362.46
References & Citations
[1]Speck AL, et al. The absolute configuration and crystal structure of the anticholinergic drug dexbenzetimide. Nature. 1971 Aug 20;232(5312):575-6.|[2]Müller-Gärtner HW, et al. Imaging muscarinic cholinergic receptors in human brain in vivo with Spect, [123I]4-iododexetimide, and [123I]4-iodolevetimide. J Cereb Blood Flow Metab. 1992 Jul;12(4):562-70.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-105545/Dexetimide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-105545/Dexetimide-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
21888-98-2
Available Sizes
Curated Selection
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