FADD (Phospho-Ser191) Colorimetric Cell-Based ELISA Kit
The FADD (Phospho-Ser191) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor FADD (Phospho-Ser191) protein expression profile in cells. The kit can be used for measuring the relative amounts of FADD (Phospho-Ser191) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on FADD (Phospho-Ser191) .
Product Specifications
Synonyms
FAS-associated death domain protein; FAS-associating death domain-containing protein; Mediator of receptor induced toxicity; Protein FADD; Fadd; Mort1
Gene Name
Fadd
UniProt
Q61160
Reactivity
Mouse
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity) . Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity) .
Molecular Weight
22960 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
FAS-associated death domain protein
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