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TOB1 (Phospho-Ser164) Colorimetric Cell-Based ELISA Kit

The TOB1 (Phospho-Ser164) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TOB1 (Phospho-Ser164) protein expression profile in cells. The kit can be used for measuring the relative amounts of TOB1 (Phospho-Ser164) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TOB1 (Phospho-Ser164) .

Product Specifications

Synonyms

Protein Tob1; Transducer of erbB-2 1; TOB1; TOB, TROB1

Gene Name

TOB1

UniProt

P50616

Reactivity

Human, Mouse, Rat

Tissue Specificity

Ubiquitous.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex (PubMed:8632892, PubMed:23236473) . Mediates CPEB3-accelerated mRNA deadenylation by binding to CPEB3 and recruiting CNOT7 which leads to target mRNA deadenylation and decay (PubMed:21336257) .

Molecular Weight

38155 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Protein Tob1

Subcellular Location

Cytoplasm. Nucleus. Only a small fraction localizes to the cytoplasm except in late S-phase where more than half of proteins become cytoplasmic.

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