MKP-1/2 (Phospho-Ser296/318) Colorimetric Cell-Based ELISA Kit
The MKP-1/2 (Phospho-Ser296/318) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MKP-1/2 (Phospho-Ser296/318) protein expression profile in cells. The kit can be used for measuring the relative amounts of MKP-1/2 (Phospho-Ser296/318) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MKP-1/2 (Phospho-Ser296/318) .
Product Specifications
Synonyms
Dual specificity protein phosphatase 1 ;3.1.3.16 ;3.1.3.48 ; Dual specificity protein phosphatase hVH1 ; Mitogen-activated protein kinase phosphatase 1; MAP kinase phosphatase 1; MKP-1; Protein-tyrosine phosphatase CL100 ; DUSP1 ; CL100 , MKP1, PTPN10 , VH1
Gene Name
DUSP1 CL100 , MKP1, PTPN10 , VH1
UniProt
P28562
Reactivity
Human, Mouse, Rat
Tissue Specificity
Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
Molecular Weight
39298 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Dual specificity protein phosphatase 1
Subcellular Location
Nucleus.
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