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Gab2 (Phospho-Tyr643) Colorimetric Cell-Based ELISA Kit

The Gab2 (Phospho-Tyr643) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Gab2 (Phospho-Tyr643) protein expression profile in cells. The kit can be used for measuring the relative amounts of Gab2 (Phospho-Tyr643) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Gab2 (Phospho-Tyr643) .

Product Specifications

Synonyms

GRB2-associated-binding protein 2; GRB2-associated binder 2; Growth factor receptor bound protein 2-associated protein 2; pp100; GAB2; KIAA0571

Gene Name

GAB2

UniProt

Q9UQC2

Reactivity

Human, Mouse, Rat

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.

Molecular Weight

74458 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC2614

Product MSDS

https://www.bosterbio.com/msds?sku=EKC2614

Other Gene Names

GRB2-associated-binding protein 2

Subcellular Location

Cytoplasm. Cell membrane.

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