EPB41 (Phospho-Tyr660/418) Colorimetric Cell-Based ELISA Kit
The EPB41 (Phospho-Tyr660/418) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor EPB41 (Phospho-Tyr660/418) protein expression profile in cells. The kit can be used for measuring the relative amounts of EPB41 (Phospho-Tyr660/418) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on EPB41 (Phospho-Tyr660/418) .
Product Specifications
Synonyms
Protein 4.1; P4.1;4.1R; Band 4.1; EPB4.1; EPB41; E41P
Gene Name
EPB41
UniProt
P11171
Reactivity
Human, Mouse
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase (PubMed:23870127) .
Molecular Weight
97017 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Protein 4.1
Subcellular Location
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Nucleus.
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