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GRK2 (Phospho-Ser685) Colorimetric Cell-Based ELISA Kit

The GRK2 (Phospho-Ser685) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor GRK2 (Phospho-Ser685) protein expression profile in cells. The kit can be used for measuring the relative amounts of GRK2 (Phospho-Ser685) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on GRK2 (Phospho-Ser685) .

Product Specifications

Synonyms

Beta-adrenergic receptor kinase 1; Beta-ARK-1;2.7.11.15; G-protein coupled receptor kinase 2 ; GRK2 ; ADRBK1, BARK, BARK1

Gene Name

GRK2

UniProt

P25098

Reactivity

Human, Mouse, Rat

Tissue Specificity

Expressed in peripheral blood leukocytes.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.

Molecular Weight

79574 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC2602

Product MSDS

https://www.bosterbio.com/msds?sku=EKC2602

Other Gene Names

Beta-adrenergic receptor kinase 1

Subcellular Location

Cytoplasm. Cell membrane.

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