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Androgen Receptor (Phospho-Tyr363) Colorimetric Cell-Based ELISA Kit

The Androgen Receptor (Phospho-Tyr363) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Androgen Receptor (Phospho-Tyr363) protein expression profile in cells. The kit can be used for measuring the relative amounts of Androgen Receptor (Phospho-Tyr363) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Androgen Receptor (Phospho-Tyr363) .

Product Specifications

Synonyms

Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4; AR; DHTR, NR3C4

Gene Name

AR

UniProt

P10275

Reactivity

Human, Mouse, Rat

Tissue Specificity

Isoform 2 is mainly expressed in heart and skeletal muscle (PubMed:15634333) . Isoform 3 is expressed by basal and stromal cells of prostate (at protein level) (PubMed:19244107) .

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.

Molecular Weight

99188 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Androgen receptor

Subcellular Location

Nucleus. Cytoplasm. Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of RACK1.

Frequently Asked Questions

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