MKK3 (Phospho-Thr222) Colorimetric Cell-Based ELISA Kit
The MKK3 (Phospho-Thr222) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MKK3 (Phospho-Thr222) protein expression profile in cells. The kit can be used for measuring the relative amounts of MKK3 (Phospho-Thr222) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MKK3 (Phospho-Thr222) .
Product Specifications
Synonyms
Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAPKK 3;2.7.12.2 ; MAPK/ERK kinase 3; MEK 3; Stress-activated protein kinase kinase 2; SAPK kinase 2; SAPKK-2; SAPKK2; MAP2K3; MEK3, MKK3, PRKMK3, SKK2
Gene Name
MAP2K3
UniProt
P46734
Reactivity
Human, Mouse, Rat
Tissue Specificity
Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14.
Molecular Weight
39318 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Dual specificity mitogen-activated protein kinase kinase 3
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