C-Jun (Phospho-Ser243) Colorimetric Cell-Based ELISA Kit

The c-Jun (Phospho-Ser243) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor c-Jun (Phospho-Ser243) protein expression profile in cells. The kit can be used for measuring the relative amounts of c-Jun (Phospho-Ser243) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on c-Jun (Phospho-Ser243) .

Product Specifications

Synonyms

Transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39; JUN

Gene Name

JUN

UniProt

P05412

Reactivity

Human, Mouse, Rat

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306) . Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306) .