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JAK1 (Phospho-Tyr1022) Colorimetric Cell-Based ELISA Kit

The JAK1 (Phospho-Tyr1022) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor JAK1 (Phospho-Tyr1022) protein expression profile in cells. The kit can be used for measuring the relative amounts of JAK1 (Phospho-Tyr1022) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on JAK1 (Phospho-Tyr1022) .

Product Specifications

Synonyms

Tyrosine-protein kinase JAK1;2.7.10.2 ; Janus kinase 1; JAK-1; JAK1; JAK1A, JAK1B

Gene Name

JAK1

UniProt

P23458

Reactivity

Human, Mouse, Rat

Tissue Specificity

Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway (PubMed:7615558) . Kinase partner for the interleukin (IL) -2 receptor (PubMed:11909529) .

Molecular Weight

133277 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Tyrosine-protein kinase JAK1

Subcellular Location

Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated.

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