IRS-1 (Phospho-Ser312) Colorimetric Cell-Based ELISA Kit

The IRS-1 (Phospho-Ser312) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor IRS-1 (Phospho-Ser312) protein expression profile in cells. The kit can be used for measuring the relative amounts of IRS-1 (Phospho-Ser312) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on IRS-1 (Phospho-Ser312) .

Product Specifications

Synonyms

Insulin receptor substrate 1; IRS-1; IRS1

Gene Name

IRS1

UniProt

P35568

Reactivity

Human, Mouse, Rat

Applications

ELISA

Detection Range

> 5000 cells/well

Function

May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity) .