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GATA1 (Phospho-Ser142) Colorimetric Cell-Based ELISA Kit

The GATA1 (Phospho-Ser142) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor GATA1 (Phospho-Ser142) protein expression profile in cells. The kit can be used for measuring the relative amounts of GATA1 (Phospho-Ser142) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on GATA1 (Phospho-Ser142) .

Product Specifications

Synonyms

Erythroid transcription factor; Eryf1; GATA-binding factor 1; GATA-1; GF-1; NF-E1 DNA-binding protein; GATA1; ERYF1, GF1

Gene Name

GATA1

UniProt

P15976

Reactivity

Human, Mouse, Rat

Tissue Specificity

Erythrocytes.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (PubMed:24245781) .

Molecular Weight

42751 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Erythroid transcription factor

Subcellular Location

Nucleus.

Frequently Asked Questions

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