GATA1 (Phospho-Ser142) Colorimetric Cell-Based ELISA Kit
The GATA1 (Phospho-Ser142) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor GATA1 (Phospho-Ser142) protein expression profile in cells. The kit can be used for measuring the relative amounts of GATA1 (Phospho-Ser142) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on GATA1 (Phospho-Ser142) .
Product Specifications
Synonyms
Erythroid transcription factor; Eryf1; GATA-binding factor 1; GATA-1; GF-1; NF-E1 DNA-binding protein; GATA1; ERYF1, GF1
Gene Name
GATA1
UniProt
P15976
Reactivity
Human, Mouse, Rat
Tissue Specificity
Erythrocytes.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (PubMed:24245781) .
Molecular Weight
42751 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Erythroid transcription factor
Subcellular Location
Nucleus.
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